Numerous studies about the pathogenic role of Helicobacter pylori(H. pylori) in gastroduodenal disease have been carried out actively and H. pylori has been strongly implicated as a cause of chronic active gastritis and duodenal ulcer. Many
detective
methods of H. pylori have been developed, but few studies have been reported about the sensitivity or applicability of these detective methods.
Therefore, we evaluate the sensitivity of detection methods for H. pylori infection in gastroduodenal disease. CLO test, Gram stain of touch print, culture, and Giemsa stain were used for the detection of H. pylori in specimens obtained by
endoscopic
biopsy of the gastric antrum from 98 patients with gastroduodenal diseases including erosive gastritis, chronic gastritis, gastric ulcer, duodenal ulcer, and gastric cancer.
In conclusion, the most sensitive method was Giemsa stain and the next was CLO test. These two methods were effective in diagnosis of H. pylori infection. CLO test was considered to be a relatively speedy and simple detective method.
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